hero-mesotherapy

Mesotherapy

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As Vanity Cosmetic Surgery Center, we work with surgeons with international certificates so that you can trust us.

Introduction: Cellular Nutrition and Skin Vitality

The skin is our largest organ and our primary shield against environmental damage. It constantly deals with natural aging, UV radiation, pollution, and hormonal changes. Over time, these factors deplete our natural pools of hyaluronic acid, essential structural proteins, and antioxidant enzymes. While advanced topical serums and luxury moisturizers play a role in surface care, they possess a major biological limit: the skin’s outer layer (the stratum corneum) is specifically designed to keep substances out, meaning up to 90% of topical ingredients can fail to reach the deep cellular layers where true rejuvenation happens.

At Vanity Cosmetic Surgery Hospital, our signature “Better You!” philosophy is built completely on clinical transparency and providing advanced, evidence-based options for your skin. When topical treatments fall short, modern aesthetic medicine bridges the gap by delivering nutrients directly where they are needed most. This definitive clinical guide explores the biological science behind advanced mesotherapy treatments, breaks down our premium range of skin boosters like Jalupro, Exosomes, and HArmonyCa, analyzes global cost structures, and explains how this walk-in outpatient protocol safely restores skin health from the inside out.

What is Mesotherapy Treatment?

Mesotherapy is an innovative, non-surgical cosmetic treatment that relies on making a sequence of micro-injections into the skin’s middle layer, known as the mesoderm. Originally developed in France, the procedure utilizes ultra-fine needles to deliver highly concentrated, customized cocktails of bio-compatible ingredients directly into the target zone.

The Micro-Injection Delivery System into the Mesoderm

By placing nutrients directly into the mesoderm, the treatment bypasses the skin’s outer barrier entirely. The physical micro-punctures trigger a natural healing cascade, stimulating local fibroblast cells to produce brand-new collagen and elastin. Simultaneously, the specialized cocktail provides these cells with the raw nutritional materials needed to rebuild a firm, resilient skin matrix.

Primary Clinical Indications: From Anti-Aging to Skin Blemishes

Because the injectable solution can be fully customized, mesotherapy is highly effective at treating a wide range of cosmetic concerns across the face, neck, décolletage, hands, and scalp:

  • Anti-Aging & Wrinkle Reduction: Smooths out fine surface lines and restores youthful elasticity.
  • Skin Blemishes & Hyperpigmentation: Fades stubborn sunspots, balances uneven skin tones, and brightens a dull complexion.
  • Vibrant Mesolifting: Tightens mild tissue sagging and restores deep cellular hydration.
  • Scar & Acne Revision: Rebuilds damaged skin texturing to soften the look of superficial scars.
  • Hair Preservation: Injected into the scalp to nourish dormant hair follicles, increase blood circulation, and combat thinning hair.
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The Premium Master Suite of Specialized Mesotherapy & Jalupro Formulae

At Vanity Cosmetic Surgery Hospital, we do not believe in a one-size-fits-all approach to skincare. Our specialists choose from a premium selection of internationally certified formulas to match your specific tissue type:

1. Targeted Anti-Aging & Skin Blemishes Cocktail

This foundational mesotherapy cocktail combines low-density non-crosslinked hyaluronic acid with organic silicium, multi-vitamins (A, B, C, E), and coenzymes. It focuses on breaking down excess pigment deposits to fade skin blemishes while boosting cell renewal to smooth out early wrinkles.

2. Jalupro Classic: The Amino Acid Foundation

Jalupro Classic is a highly technical amino acid replacement therapy designed specifically for skin that is beginning to lose its youthful bounce. The formula provides a precise, scientifically proven cluster of vital amino acids (Glycine, L-Proline, L-Lysine, L-Leucine). These are the exact structural ingredients your fibroblast cells require to generate new collagen, effectively thickening thin skin and improving texture.

3. Jalupro Hydro: Precision Lifting & Hydration

For skin requiring significant hydration and subtle lifting, Jalupro Hydro combines high-molecular-weight hyaluronic acid with targeted biomimetic peptides. This combination provides a powerful “lifting & hydration” effect. It locks in moisture deeply, smooths fine lines, and lifts relaxed skin folds, making it an excellent option for smoothing the face, neck, or under-eye areas.

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Advanced Biological Boosters and Cellular Regenerators

When skin requires a more powerful form of tissue regeneration, our medical teams utilize advanced, cell-signaling biological treatments:

1. Skin Exosome Therapy: Advanced Cellular Messenger Systems

Exosome therapy represents an innovative milestone in non-surgical cellular restoration. Exosomes are microscopic extracellular vesicles that function as powerful messengers between cells, carrying high concentrations of growth factors, lipids, and signaling proteins.

When micro-injected into compromised skin tissue, exosomes communicate directly with dormant or damaged cells, signaling them to accelerate repair, reduce chronic localized inflammation, and boost healthy cell renewal. It is an exceptional solution for erasing deep sun damage and correcting skin blemishes.

2. Salmon DNA (Polynucleotide Repair)

Formulated with highly purified polynucleotide chains extracted from salmon trout DNA, this regenerative booster is exceptionally bio-compatible with human tissue. Salmon DNA works by binding directly to water molecules to provide deep hydration, while simultaneously signaling fibroblast cells to repair damaged structural tissue, restore skin elasticity, and calm redness.

3. HArmonyCa: The Dual-Effect Hybrid Filler

For patients experiencing volume loss alongside surface wrinkles, HArmonyCa is a premier hybrid injectable. It combines a smooth Hyaluronic Acid gel with Calcium Hydroxyapatite (CaHA) microspheres in a single syringe. The HA gel provides an immediate lifting effect to smooth out folds, while the CaHA particles release deep into the tissue over several months to continuously stimulate your body’s own natural collagen production, providing long-term skin thickening.

4. Direct Collagen Injections

This option introduces pure, bio-compatible collagen building blocks directly into the dermal matrix. It instantly replaces degraded structural fibers, reduces fine lines, and creates a beautifully firm, smooth surface texture.

Systemic Metabolic Restoration: Clinical Ozon Therapy

To complement our localized mesotherapy treatments, Vanity Cosmetic Surgery Hospital offers clinical Ozon Therapy through a comprehensive 10-session protocol.

Dark circles, dull skin, and chronic skin blemishes can often stem from systemic issues like poor blood oxygenation, slow cell metabolism, or accumulated toxic stress. Medical-grade ozone therapy works systemically by optimizing your body’s oxygen delivery, improving blood circulation, boosting cellular energy production, and enhancing natural detoxification pathways. This metabolic support helps you achieve a beautifully radiant, healthy complexion from the inside out.

Global Cost Analysis: Premium Private Clinics vs. Türkiye

The cost of advanced mesotherapy and skin booster treatments varies based on the specific formula used, the size of the treatment area, and the number of sessions required. Below is an overview of high-end private healthcare pricing per session compared to Vanity Cosmetic Surgery Hospital.

 

Treatment Variant & CountryEstimated Premium Private Price Range (Per Session)
United States $1,200 (€1,100)
EuropeCHF 950 (€980)
United Kingdom £850 (approx. €980)
Vanity Cosmetic Surgery Hospital (Türkiye)Premium Mesotherapy starts from €149

Note: Pricing reflects per-session starting templates for certified, international brands inside our accredited medical facility

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The Mesotherapy Treatment Recovery Timeline

The primary benefit of a mesotherapy treatment is its minimal impact on your daily routine:

  • The Injection Session (20 to 45 Minutes): A topical numbing cream is applied to ensure a comfortable experience. The doctor then performs a sequence of swift micro-injections across the targeted zones.
  • The First 24 to 48 Hours: Your skin will look slightly pink, flushed, and may show tiny raised bumps at the injection sites, which is a normal response as the nutrients absorb into the tissue. Mild swelling or pinpoint bruising can occur but resolves rapidly. You should avoid applying heavy makeup or touching your face for the first 24 hours to keep the entry points clean.
  • The Settling Process: Within 2 to 3 days, your skin becomes completely smooth, and a refreshed, deeply hydrated glow begins to surface. For optimal, long-term correction of wrinkles or skin blemishes, a structured course of 3 to 5 sessions spaced two weeks apart is generally recommended.

Essential Safety Protocols and Preventative Care

While mesotherapy is a safe, non-surgical treatment, we maintain high safety standards to prevent side effects:

  • Allergy Screenings: Our pre-treatment assessment ensures you have no sensitivities to any vitamins or active ingredients within the custom mix.
  • Expert Handling: Injections are performed exclusively by qualified medical aesthetic doctors or plastic surgeons using precise depths, completely eliminating the risks of tracking or surface scarring associated with uncertified salons.
  • Infection Prevention: Treatment cannot be performed over active cystic acne, open wounds, or active skin infections until the tissue has fully healed.

Many international patients choose to combine their custom skin booster sessions with other quick, non-surgical enhancements during their visit, such as Lip Augmentation (like the vertical Russian Lips technique), Non-Surgical Rhinoplasty (Liquid Nose Jobs), or targeted Redensity under-eye light filling to brighten their entire facial profile.

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International Travel Logistics (Walk-In Outpatient Care)

For international patients traveling to Türkiye from the UK, Europe, the USA, or Canada, advanced mesotherapy offers a highly convenient, zero-downtime treatment path.

  • No Hospital Stay Required: The entire treatment is performed on a walk-in, walk-out outpatient basis. You are completely free to enjoy sightseeing in Istanbul or return home immediately following your session.
  • No Air Travel Restrictions: Dermal boosters introduce zero post-procedure flight limitations; you are medically safe to board your flight home on the very same day.

Your “Better You” Journey: Strategic Next Steps

Whether you are looking to erase stubborn skin blemishes using custom mesotherapy, lift and hydrate your skin with Jalupro Hydro, or explore deep cellular regeneration with advanced Exosomes, our medical team is here to guide you with absolute honesty.Take the first step toward healthier, more vibrant skin. Connect with our care coordination team today to ask a doctor a question or book your initial clinical examination and diagnostic blood panel.

Our Mesotherapy Doctors

Vanity Estetik Doktoru Güray Yeşiladalı
Güray Yeşiladalı, M.D.
Plastic, Reconstructive and Aesthetic Surgery

Personal Details

  • Officially appointed expert in the field of plastic surgery, Highly experienced plastic surgeon specialising in breast and buttock enhancements, rhinoplasty, liposuction, fat transfer procedures.
  • Graduated from Istanbul University Cerrahpaşa Faculty of Medicine.
  • Won the Turkish-German Medical Association Scholarship and had the chance to study in Giessen University, Germany.
  • He started his Plastic Surgery residency in Haydarpasa Numune Training and Research Hospital in Istanbul.
  • Apart from performing thousands of plastic surgery operations, he was accepted as an International Fellow to Wisconsin University, Department of Plastic and Reconstructive Surgery in United States, and had the chance to improve his surgical skills, experience and international communication abilities.

Certifications and professional memberships

  • International Society of Plastic, Reconstructive and Aesthetic Surgery (ISAPS),
  • Aesthetic Plastic Surgery Association (EPCD),
  • Fellow of the European Society of Plastic, Reconstructive and Aesthetic Surgery (FEBOPRAS)
  • Istanbul Medical Chamber
  • Rhinoplasty Society of Europe

Other

  • Performing thousands of plastic surgery operations.
  • Founder of Vanity Cosmetic Surgery Center(2016).
Op. Dr. Bora Ok
Bora Ok, M.D.
Plastic, Reconstructive and Aesthetic Surgery

Personal Details

  • MD. Bora Ok completed his medical education with honors at Karadeniz Technical University Faculty of Medicine.
  • He began his professional career by receiving specialization training in the field of Plastic, Reconstructive, and Aesthetic Surgery at Istanbul Haydarpasa Training and Research Hospital.
  • During his specialization training, he participated in numerous hand surgeries, burn treatments, congenital anomaly corrections, microsurgery procedures, tumor surgeries, and aesthetic surgical operations.
  • He successfully completed a microsurgery course organized by the Reconstructive Microsurgery Association at Dokuz Eylül University.
  • Member of International Society of Aesthetic Plastic Surgery (ISAPS) and more.
  • Speaks fluent English.

Certifications and professional memberships

  • American Society for Aesthetic Plastic Surgery (ASAPS)
  • American Society of Plastic Surgeons (ASPS)
  • International Society of Aesthetic Plastic Surgery (ISAPS)
  • Rhinoplasty Society of Europe (RSE)
  • Aesthetic Plastic Surgery Association
  • Turkish Plastic Reconstructive and Aesthetic Surgery Association
  • Turkish Medical Association

Other

  • MD. Ok is renowned for his expertise in ethnic rhinoplasty and closed rhinoplasty procedures.
  • He uses state-of-the-art methods to achieve exceptional results in breast augmentation, breast lifts, neck lifts, facelifts, eyelid surgery, body shaping, liposuction, tummy tuck, and mommy makeover procedures.
  • Dr. Ok’s approach to patient care is highly personalized, taking into consideration each patient’s needs and expectations. He is deeply commited to providing his patients with the highest quality of care and achieving outstanding results. After closely listening to their wishes and goals, he creates a realistic framework that puts them on the path to achieving their dreams.
Doç.Dr Selami Serhat Şirvan
Prof. Dr. Selami Serhat Şirvan
Plastic, Reconstructive and Aesthetic Surgery
sinem-eroglu
Prof. Dr. Sinem Eroğlu
Plastic, Reconstructive and Aesthetic Surgery

Personal Details

  • Graduated from Marmara University Faculty of Medicine in English in 2000,
  • Completed her residency in the field of Plastic, Reconstructive and Aesthetic Surgery at Haydarpaşa Numune Training and Research Hospital in 2006.
  • In 2012 by being successful in written and oral exams and has received a professor title in 2022.
  • Assumed the administrative responsibility for University of Health Sciences Haydarpaşa Numune Training and Research Hospital between 2012 and 2021.

Certifications and professional memberships

  • International Society of Plastic, Reconstructive and Aesthetic Surgery (ISAPS).
  • Fellow of the European Board of Plastic, Reconstructive and Aesthetic Surgery(FEBOPRAS).

Other

  • Prof. Dr. Sinem Eroğlu, who has more than 50 articles and more than 100 announcements that were published in the international and national scientific journals.
  • Accept her clients in Vanity Cosmetic Surgery Center since 2022.
  • Working at Vanity Cosmetic Surgery Center since 2022
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Can Zeliha Gül, M.D.
Plastic, Reconstructive and Aesthetic Surgery

Personal Details

  • Dr. Can Zeliha Gül completed her medical training at Istanbul University Faculty of Medicine (Çapa Medicine) in 2011.
  • M.D. Gül began her professional career by receiving specialization training in Plastic, Reconstructive, and Aesthetic Surgery at Şişli Etfal Research and Training Hospital, where she worked between 2011 and 2017.
  • From 2017 to 2019, she served in the field of Plastic Surgery at Gaziantep Nizip State Hospital.
  • She worked at Vanity Cosmetic Surgery Center from 2019 to 2021, further enhancing her knowledge and experience in the field of aesthetic surgery.

Certifications and professional memberships

  • Fellow of the European Board Of Plastic, Reconstructive And Aesthetic Surgery (FEBOPRAS)
  • Turkish Plastic, Reconstructive And Aesthetic Surgery Association (TPRECD)
  • Aesthetic And Plastic Surgery Association (EPCD)
  • Turkish Doctors Assoc. (TTB)
  • International Society Of Plastic Surgery (ISAPS)

Other

  • In August 2023, she rejoined the team at Vanity Cosmetic Surgery Center. She aims to provide patients with the highest quality healthcare utilizing her knowledge and skills in the field of aesthetic and reconstructive surgery to enhance their quality of life.
mert-sizmaz
Mert Sızmaz, M.D.
Plastic, Reconstructive and Aesthetic Surgery

Personal Details

  • Graduated at Istanbul University Cerrahpaşa Faculty of Medicine, Department of Medicine in English.
  • Specialty training at Şişli Hamidiye Etfal Training and Research Hospital.
  • In 2019 he was in the United States as part of the observership program.
  • He completed his compulsory service at Kars Harakani State Hospital.

Certifications and professional memberships

  • Turkish Plastic, Reconstructive and Aesthetic Surgery Association (TPRECD)
  • Fellow of the European Board of Plastic, Reconstructive and Aesthetic Surgery(FEBOPRAS)
  • Istanbul Medical Chamber
  • Turkey Aesthetic Plastic Surgery Society
  • Turkish Doctors Assoc.

Other

  • He had the opportunity to experience many surgeries at Tampa General Hospital.
  • He has publications in many national and international journals.
  • Working at Vanity Cosmetic Surgery Center since 2023.
Op. Dr. Çağatay Öner
Çağatay Öner, M.D.
Plastic, Reconstructive and Aesthetic Surgery

Personal Details

  • Dr. Çağatay Öner completed his medical education at Istanbul University Cerrahpaşa English Faculty of Medicine in 2014.
  • He completed his Plastic, Reconstructive, and Aesthetic Surgery specialist training, which he started in 2015, at Şişli Hamidiye Etfal Training and Research Hospital in 2020.
  • In 2019, he participated in an observership program in Germany to enhance his experience in the field of Aesthetic Surgery.
  • He worked in the field of Plastic Surgery at Şırnak State Hospital between 2020-2022.

Certifications and professional memberships

  • Turkish Society of Plastic, Reconstructive, and Aesthetic Surgery (TPRECD)
  • Fellow of the European Board of Plastic, Reconstructive, and Aesthetic Surgery (FEBOPRAS)
  • Turkish Doctors Assoc.

Other

  • He has publications in various national and international journals.
  • His hobbies include nature photography, skiing, scuba diving, and trekking.

Frequently Asked Questions

The treatment is highly comfortable. We apply a strong, medical-grade topical numbing cream to the treatment area for 20 to 30 minutes prior to the session. The injections are placed using ultra-fine micro-needles, so most patients describe the sensation as a light, brief tingling or pinching rather than actual pain.
Jalupro Classic focuses primarily on providing an amino acid blueprint to jumpstart collagen production, making it ideal for improving skin texture and thinning tissue. Jalupro Hydro combines targeted peptides with high-molecular-weight hyaluronic acid to provide an intensive "lifting & hydration" effect, making it perfect for deeper wrinkles and dry skin.
While a beautiful, hydrated glow is often visible within a few days of your very first session, achieving long-term correction for skin blemishes, deep wrinkles, or hair thinning typically requires a structured course of 3 to 5 sessions, spaced approximately 2 weeks apart.
Yes. Scalp mesotherapy is a highly effective treatment for hair preservation. By injecting a specialized mix of vitamins, minerals, and vasodilators directly around the hair roots, the treatment improves local blood circulation, delivers nutrients to dormant hair follicles, and helps slow down pattern thinning in both men and women.
HArmonyCa is a premium hybrid injectable that combines a cross-linked Hyaluronic Acid gel with Calcium Hydroxyapatite (CaHA) microspheres. The HA gel provides an immediate lift to smooth out skin folds, while the CaHA particles work deep within the tissue over the following months to stimulate your body's own natural collagen production for long-term firmness.
Patient safety is our primary focus. The €70 fee covers a comprehensive face-to-face consultation with our medical specialist along with detailed blood laboratory diagnostics. This step ensures you have no underlying medical exclusions, checks your cellular health, and allows us to formulate a custom mesotherapy mix perfectly matched to your body's unique metabolism.
Emre Erol, M.D.

About The Author

Created By
Publish Date
Update Date
Emre Erol, M.D.
26/10/2022
03/08/2026

Dr Erol holds an M.D. from Istanbul University Cerrahpaşa (2006) and a Family‑Medicine specialty from Medeniyet University. After 16 years of combined clinical and managerial roles within the Ministry of Health, he joined Vanity in 2022 as Deputy General Manager for Administrative & Medical Affairs. He bridges clinical governance with patient‑safety oversight, ensuring protocols align with Turkish MoH and international accreditation standards.

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